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                        斑馬魚命名規則

                        完整的斑馬魚命名規則請見斑馬魚命名規則(中英文對照).pdf

                        以下為常用的斑馬魚品系命名規則:

                        Line Designations

                        斑馬魚品系命名

                        Each institution that produces fish lines should acquire an institutional line designation. Historically, line designations were assigned to labs, but the proliferation of labs producing fish has resulted in a change to assigning the designations on an institutional basis. All labs producing fish lines at the same institution should seek to share a single institutional line designation.

                         

                        每一家創制斑馬魚品系的機構都需要申請一個機構命名的品系名稱(機構命名代碼)。在過去,品系是以實驗室為基礎命名的,但是由于實驗室數量增長,現在品系命名系統以實驗室所屬機構為基礎。同屬一家機構的實驗室應當協商產生一個共同的機構品系名稱(機構命名代碼)。

                         

                        Contact the Nomenclature Coordinator to be assigned a new line designation. Line designations are assigned using these guidelines:

                        ·       A 2-letter designation is preferred, but is not always possible. In that case a 3-letter designation must be chosen.

                        ·       The designation must not conflict with any zebrafish, human or mouse gene or phenotypic designations.

                        ·       The designation must not conflict with any other line designations. For example, t is listed as the designation for Tubingen, but they use most 2-letter designations that begin with "t".

                         

                        申請新的品系名稱,請聯系命名協調員。在命名時請參考以下指南:

                        ·       機構命名代碼首選2個字母的名稱;其次再考慮3個字母的名稱。

                        ·       機構命名代碼不得與任何斑馬魚、人類或小鼠基因名稱或表型名稱相沖突。

                        ·       名稱命名代碼不得與其他已有的名稱沖突。例如,t已被注冊為Tubingen的代碼,但以“t”開頭的大多數2個字母組合名稱仍可使用。

                         

                        Allele-specific names for zebrafish mutants are denoted by superscript following the mutant locus symbol. They are formed by the following rules:

                        ·       Dominant mutations are indicated by a d in the first position; a name without a d indicates a recessive allele.

                        ·       The superscript contains a lower-case letter designation corresponding to the institution at which the mutation was isolated (see table below). This will occur either at the beginning of the name (if recessive) or immediately after the d (if dominant).

                        ·       The institution identifer is followed by a unique number for the particular line.

                        ·       Additional letters should not immediately follow the institution designation but may be appended to the number at the end of the name.

                        ·       Only alphanumeric characters should be used in the line designation.

                        ·       Each allele number must be unique. Because each institution has a different letter designation, all lines are uniquely identified. Click on a designation below to see a list of all lines currently associated with that institution.

                         

                        斑馬魚突變的特定名稱應以上標表示,緊跟所突變的基因名稱之后。具體規則如下:

                        ·       命名若以d開頭則表示該突變為顯性突變;否則為隱性突變。

                        ·       當突變名稱僅含有一個字母時,這個字母表示創制該突變的機構命名代碼(清單見下),如果突變為隱形,則以該字母開頭,如突變為顯性則在前面加d

                        ·       機構命名代碼其后應跟著唯一的數字編號。

                        ·       (如需增加字母后綴)字母后綴不能緊跟機構命名代碼,而應該附加在編碼之后。

                        ·       品系命名只能使用字母和數字。

                        ·       每個等位基因的編號必須是唯一的。由于每個機構都有不同的機構命名代碼,因此所有品系都是唯一標識的。檢索下面的清單表格可以查找全部已有的機構命名代碼。





                        For example, in Eugene, Oregon, all allele names begin with b and are numbered sequentially, approximately in the order that they were identified; cycb16 is an allele of cyclops that was isolated in Eugene.

                        More examples:
                        Dominant allele from Carnegie Institute - chidc124
                        Recessive alleles from Children's Hospital, Boston - dlycz3321, egycz5
                        Recessive allele from University of Pennsylvania, with appended letters - bbpp58cd

                         

                         

                        For more information, you can refer to the Zebrafish Nomenclature Guidelines. To request a new letter designation for your laboratory, please contact ZFIN.

                         

                         

                         

                        例如,對于美國俄勒岡州尤金市,所有創制的等位基因名稱都以b開頭,并按等位基因被創制的順序編號;cycb16是表明這是尤金的研究者創制的cyclops這個基因的突變。

                        更多例子:

                        來自卡內基研究所(Carnegie Institute)的顯性突變: chidc124

                        來自波士頓兒童醫院(Children's Hospital, Boston)的隱性等位基因:dlycz3321, egycz5

                        來自賓夕法尼亞大學(University of Pennsylvania)的隱性等位基因,它的名稱中帶有字母后綴: bbpp58cd

                        有關更多信息,請參閱斑馬魚命名規則。如您要為實驗室申請新的品系名稱,請聯系ZFIN


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